Autori: Bhattacharya, Rahul, Shome, Madhumita
Titolo: A randomized two stage allocation for continuous response clinical trials
Periodico: Statistical methods & applications : Journal of the Italian Statistical Society
Anno: 2015 - Volume: 24 - Fascicolo: 3 - Pagina iniziale: 373 - Pagina finale: 386

A randomized two treatment allocation design, conducted in two stages, is proposed for a class of continuous response trials. Patients are assigned to each treatment in equal numbers in the first stage and p value of a test of equality of treatment effects based on these data is used to determine the assignment probability of second stage patients. Relevant properties of the proposed allocation design are investigated and compared with suitable competitors.




SICI: 1618-2510(2015)24:3<373:ARTSAF>2.0.ZU;2-N

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